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Description

J Zoo Wildl Med 29(1):18-20, 1998

Via the activation of TLR4/MAPK signaling in KCs ( In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis