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10.1016/j.freeradbiomed.2022.02.017 100 HassaneinE

Moreover, most clinical trials continue to rely on liver enzymes and imaging endpoints without stratifying patients according to inflammatory phenotype or cytokine signatures

Although Free T3 rises earlier in hyperthyroidism than Free T4 and is thus a more sensitive test, levels are particularly susceptible to non-thyroidal influences which alter peripheral T4 to T3 conversion

These comments echoed the sentiments expressed by the commenters on the same topic in the 2014 final rule mentioned above, and while they were out of the scope of our proposals for CY 2022, we will elaborate on them here