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In contrast, further studies showed that the density of MOR-like immunoreactivity is significantly reduced in the ipsilateral dorsal horn (laminae I and II) L4/5 segment after L4/5 SNL in SD rats [99], and similar studies have found that the expression of MOR protein in the L4/5 spinal cord segment decreased from the 35th day of ligation in the L5 SNL model of rats [100]

Because iron is indispensable for wrapping myelin and powering metabolic enzymes, oligodendrocytes outrank every other CNS cell population in intracellular iron content (Friedrich et al., 2021

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Consistency is generally more important than the specific hour, so choose a time you can stick to every day