glutathione for elderly Frontiers Glutathione: A Samsonian life-sustaining small

3 Interactions of autophagy with the cGAS-STING pathway 3.1 cGAS The interplay between autophagy and cGAS occurs through (i) cGAS-Beclin-1 interaction that promotes autophagic degradation of cytosolic dsDNA, (ii) cGAS-LC3 interaction that promotes micronucleophagy, and (iii) degradation of cGAS through p62-mediated selective autophagy ( Figure 3 )

The GHK might separate from the copper ion

Molecular graphics were generated using PyMOL as previously described (61)

The cell-killing effect of BSO&OXA@MOF-LR was markedly increased compared to that of BSO@MOF-LR or OXA@MOF-LR, indicating the synergistic effect of ferroptosis inducer and chemotherapeutic drug (Additional file 1: Fig