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yoelii cultures with XO in the presence of the antioxidant enzyme catalase restored the virulence of the parasite, indicating that XO-produced ROS interfered with its survival within the host ( Phagocytic Oxidative Burst The production of ROS is a crucial part of the host response to various infectious agents, including Plasmodium

Abdulbaqi IM, Assi RA, Yaghmur A, Darwis Y, Mohtar N, Parumasivam T, et al

52 Consequently, a novel regulation mode of lactylation using lactate as a direct donor without necessitating the formation of lactyl-CoA is proposed, expanding the substrate range of lactylation

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