glutathione s transferase pathway The role of glutathione-S-transferase in anti-cancer drug resistance Insights into the Catalytic Mechanism

:Basic cofactors consist of: Vitamins A and Vitamin D (11,000 IU and 3000 5000 IU respectively) Vitamin C at 4000+ mg per day Vitamin E B vitamin complex with P5P, biotin and pantethine (without including cyano B12 or folic acid) A 1:1 magnesium:calcium supplement Zinc, 50 mg per day Omega 3 fatty acids, 2-6 caps per day Optional Basic Cofactors include: Glycophospholipids Additional pantethine Multimineral supplements (choline, selenium) Alpha lipoic acid D-Ribose CoQ-10 Titrate B12s while adjusting methylfolate and potassium Methylcobalamin (MeB12) should start at 15-20 mg per day Adenosylcobalamin (AdoB12) should start at 10 mg per week Titrate methylfolate to sufficiency, starting at 1 mg Titrate L-carnitine fumarate (LCF) to effectiveness, starting at 125 mg per day and aiming for 500-1000 mg per day, stopping when an increase of 250 mg makes no difference

In a crossover trial of tyrosine in Zung scale depression, a woman unable to tolerate standard antidepressant therapy was given 70 100 mg/kg of tyrosine in 3 daily doses for 2 weeks, a placebo for 18 days, then tyrosine 60 again for a further 5 weeks

Several vitamin deficiencies can contribute to joint and knee discomfort

J Clin Aesthet Dermatol 2016;9:214