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The advantages include the absence of surgical intervention, low risk, and fewer complications, with most patients not experiencing recurrent leaks or fistulas after endoscopic treatment

Throughout these disease processes, ROS-mediated impairment of antioxidant defense systems and pro-survival pathways further amplifies the neurodegeneration cascade [339]

Our studies highlight the selective regulation of an acyl-lipoyl conjugate (thioester bond), which is distinct from the role of Sirtuins (SIRTs) in cleaving acyl modifications from lysine residues (amide bonds)

Very common (may affect more than 1 in 10 people): mild redness, slight stinging, or tight feeling for the first few days