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Paracetamol is a widely-used over-the-counter medicine thats effective for the treatment of fever and mild to moderate pain

coli SHuffle T7 (New England Biolabs) cells, which were then spread on an LB agar plate (100 g/mL ampicillin)

Albert BB, Derraik JG, Brennan CM, Biggs JB, Smith GC, Garg ML,

Later experiments have found that adding high doses of copper can increase reactive oxygen species and protein carbonylation levels, decrease glutathione levels and SOD enzyme activity, leading to depolarization of mitochondrial membrane potential, the release of cytochrome c, elevated levels of active caspase-9 and caspase-3, increased levels of Bcl2-antagonist/killer 1 (Bak1) and Bcl2-associated X protein (Bax), and decreased levels of B-cell lymphoma 2 (Bcl2), ultimately resulting in cell apoptosis (134)