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In double-blind, placebo-controlled trials, daily application of GHK-Cu cream at 3% concentration for 12 weeks produced a 70% increase in skin collagen thickness as measured by ultrasound imaging, a 40% increase in skin elasticity, and visible reduction in fine lines and wrinkles

While not a substitute for medical evaluation, this data can inform decisions about continued use

What that tells me as a clinician: AOD-9604 is not a stand-alone weight-loss strategy for someone with significant excess weight

However, ignoring the potential glutathione for skin side effects or choosing unverified treatments can do more harm than good