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Investigating their association with PCOS-related metabolic and reproductive abnormalities will help uncover potential metabolic substances involved in the pathological process of PCOS, thus enriching our understanding of the relationship between gut microbial metabolites and the disorder

To clarify these observations, here, we report a functional decline of GABA INs in the SM cortex of SMA mice assessed by reduction in the number and signalling of GABAergic neurons, changes in the expression and distribution of the GABA-synthesizing enzymes (GAD) and its precursor, Gln, as well as alterations in the density and morphology of PV+ INs

AJP Endocrinol

Joannas work focuses on identifying microbiota- and gene-based biomarkers to better understand and support individuals affected by depression, MASLD, metabolic dysfunction, and emotional eating