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Although a large number of preclinical studies have achieved ideal results in material design, mechanism selection, delivery, and therapeutic effects, the inability to translate these results into clinical applications is one of the reasons why nanomaterials are rarely used in the treatment of bacterial pneumonia

BPC-157 primarily modulates the nitric oxide system and promotes VEGF-mediated angiogenesis, while TB-500 acts through actin sequestration to promote cell migration and activates integrin-linked kinase (ILK) to support cell survival

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[16] Galano A, Alvarez-Idaboy JR