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188 These genes are specifically expressed on the apical membrane of renal proximal tubule cells, which are crucial for the secretion of uric acid into the glomerular filtrate, as depicted in Fig

In the recent years, the CRISPR-dCas9 system is poised to become the most promising targetable epigenome-editing tools

doi:10.1002/jcp.27570

Overexpression of growth factors like VEGF, EGF, and IGF activates the PI3K-AKT-mTOR signaling pathway by binding to RTKs on tumor cells, regulating HIF- expression and translation, and causing its accumulation (184186)