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On the immunology side, AS is tightly linked to inflammatory signaling networks, particularly TNF- and the IL-17/IL-23 axis, which is consistent with the effectiveness of biologic therapies targeting these pathways in many patients

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But using the right amount and in the right form matters

The LPS pathway involves the metabolism of lactose into glucose and galactose, while LPPDPS breaks down lactose into glucose and galactose-6-phosphate through the hydrolysis activity by -galactosidase enzyme (Harutoshi, 2013