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Chemicals: Solvents, inorganic salts, and organic reagents were purchased from commercial sources such as Sigma and Fisher and used without further purification unless otherwise noted

Tadashi Isa (Kyoto University Graduate School of Medicine, Department of Neuroscience) for their invaluable supports of the research

Of note, the use of short-acting opioids to manage OWS in the United States during the fentanyl era has been limited to the hospital setting, given federal law restricting the use of full-agonist opioids to treat OUD outside of a federally certified OTP

In particular, cluster 4 was suggested to contain both B cells and erythrocytes using the Teefy et al