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Overall, these findings strongly suggest that the interaction between PGC-1 and NXF1 plays an important role in the nuclear export of mRNA, and inhibiting PGC-1 weakens the functional interaction of this relationship (Fig

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At the same time, alpha-tocopherol is a potent antioxidant that protects the sperm membrane from lipid peroxidation

Although reactive oxygen and nitrogen species are involved in numerous physiological processes, their excess causes damage to lipids, proteins, cell membranes or DNA (Tsukahara, 2007)