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doi: 10.1001/jamainternmed.2020.0994

10.1097/00006534-200005000-00019 81 NumataY.TeruiT.OkuyamaR.HirasawaN.SugiuraY.MiyoshiI.et al (2006)

If the drug is hydrophilic with high aqueous solubilityfor example, cromolyn sodium or neomycin, then dissolution is rapid and RDS in the absorption of such drugs is rate of permeation through the biomembrane