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Chao, C

Given the indispensable role of PINK1 in the initiation of mitophagy, there is the possible modification of ROS on PINK1 in the process of mitophagy 102

Subchondral bone plays a vital role in maintaining the homeostasis of weight-bearing joints, and the destruction of the subchondral bone can eventually result in the degeneration of the articular cartilage