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Fonctions biochimiques [modifier | modifier le code] La fraction biodisponible (transcobalamine II ou holo-TC-II) est transforme dans les cellules des tissus priphriques en deux formes coenzymatiques actives : la mthylcobalamine et l'adnosylcobalamine (synonyme de cobamamide), d'o l'existence de plusieurs rles mtaboliques majeurs [34]