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A 2022 study in Diabetes, Obesity and Metabolism showed that NNMTi treatment combined with reduced-calorie diet "promoted dramatic whole-body adiposity and weight loss in diet-induced obese mice, rapidly normalizing" weight parameters

In androgenetic alopecia (the pattern hair loss most people are dealing with), follicles progressively miniaturize and spend more time in telogen and less in anagen

The technique is contraindicated in pregnancy and breastfeeding, in active acne or skin infection, within 6 months of oral isotretinoin, in patients with keloid scarring history, and on anticoagulant therapy without physician clearance

(2019b)