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No nucleotide polymorphisms were detected in the psbA sequence of KCTR plants (Figure 3)

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While Nfr2 and HO-1 are recognized inhibitors of NF-B, this specific mechanism was not discussed in the study (Dang et al., 2022)

4.3 Renal fibrosis and extracellular matrix remodeling Renal fibrosis is the common pathological endpoint of various chronic kidney diseases (CKD) and is characterized by fibroblast activation, epithelial-to-mesenchymal transition (EMT), and abnormal accumulation of the extracellular matrix (ECM), ultimately leading to nephron destruction and loss of function ( -SMA and collagen I, promoting interstitial remodeling