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They may function, like any other type of macrophage, either in a resting, homeostatic, anti-inflammatory mode, or, on the contray, in an activated, pro-inflammatory one (169, 170) susceptible of amplifying and prolong a peripheral inflammation-induced neuroinflammation

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Cystitis A recent study on 65 people with rosacea at Johns Hopkins University and published in the American Academy of Dermatology identified associations between rosacea and urogenital diseases such as urinary tract infection (cystitis)

The transition of MMs from an anti-inflammatory to a pro-inflammatory state may contribute to the inflammatory mechanisms underlying various gastrointestinal disorders, including functional conditions such as diabetic gastroparesis, postoperative intestinal obstruction, and irritable bowel syndrome, as well as organic diseases like inflammatory bowel disease (Choi et al., 2024)