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Concurrently, the authors have noted an association between E-cadherin and -catenin, implying that the reduction in E-cadherin and the elevation of -catenin may complement each other, primarily in the maintenance of intercellular adhesion (Monga et al., 2001)

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Other fertility supplements such as L-carnitine and coenzyme Q10 may also play a role

The decondensed paternal DNA then expand to approximately three times the size of the mature sperm nucleus, resulting in the formation of the paternal pronucleus, compatible with DNA replication and the fusion of the maternal and paternal pronuclei