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Biomaterials 255 , 120200 (2020)

WebMD suggests up to 500mg per day of oral glutathione is possibly safe

Effects of Suppressing Bioavailability of Insulin-Like Growth Factor on Age-Associated Intervertebral Disc Degeneration

For many adults, 2,000 mg falls within the 20-40 mg/kg research-backed range for skin goals and is generally considered safe for short-term to medium-term use