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Study Limitations Although this pilot exploratory study provides proof-of-concept that GlyNAC supplementation from a younger age can increase length of life, the main limitation is that the study was done in a relatively small number of mice, and data is not reported from every organ in the body

Available at NC3Rs.org.uk

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Heterogeneity across the methods of different studies which include alterations in sample collection, data analysis, and sequencing techniques adds a further layer of complexity in drawing appropriate conclusions