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A.Marin-NetoJ

Through AMPK activation, metformin increases the expression of ATP-binding cassette transporter A1 (ABCA1), a key transporter involved in cholesterol efflux and apolipoprotein E (ApoE) function, which is critically implicated in AD progression [195]

Biomed Res Int 6(2020):7239895

Indeed, it was complex research balance studies that led to recommendations for a mild reduction in zinc and a significant reduction in copper from the 1979 guidelines