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HORMONE AND METABOLIC MODULATORS The following hormone and metabolic modulators are prohibited: Aromatase inhibitors including, but not limited to: 2-Androstenol (5a-androst-2-en-17-ol) 2-Androstenone (5a-androst-2-en-17-one) 3-Androstenol (5a-androst-3-en-17-ol) 3-Androstenone (5a-androst-3-en-17-one) 4-Androstene-3,6,17 trione (6-oxo) AminoglutethimideAnastrozole Androsta-1,4,6-triene-3,17-dione (androstatrienedione) Androsta-3,5-diene-7,17-dione (arimistane) Exemestane Formestane Letrozole Testolactone Anti-estrogenic substances (anti-estrogens and selective estrogen receptor modulators (SERMS))

For infusion providers, these changes can compress reported revenue and reduce spread economics on selected therapies, although the effect on gross profit dollars is often less severe because drug revenue is largely pass-through

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