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[PubMed: 908155] 396

eLife 11 , e72381 (2022)

As cellular metabolism is depleted, several non-Krebs cycle sources of carbohydrates are recruited to compensate for the loss of -KG

Earlier, we introduced the concept that cells need to first make redox investment (by supplying NADPH to reduce cystine to cysteine) in order to obtain cysteine for its subsequent utilization in redox maintenance