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These results suggest that IL-33 released from astrocytes could activate microglia and mast cells in the brain, as IL-33 is a strong activator of mast cells (Hudson et al., 2011)

R., Childs, B., Kinzler, K

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Taken together, these results thus show that Cys4p activity is reduced in the presence of Mck1p but increased in the absence of Mck1p, suggesting that Mck1p inhibits directly or not Cys4p activity, and that Mck1p kinase activity is required