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If you work in a high-stress or emotionally difficult job (for example, paramedics, firefighters, social workers, etc.), it may also be helpful to talk about a return to work with your pain psychologist

44,45 Estrogen appears to modulate pain perception in multiple ways, including through effects on nerve pathways and neurotransmitter function, influencing serotonin, dopamine, epinephrine, and endogenous opioid signaling