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To systematically elucidate the critical interplay between metabolic reprogramming and T cell fate in autoimmunity, this section focuses on RA, MS, IBD, and SLE

A 2022 study investigating berberines antimicrobial properties found that it slows bacterial metabolism, stops them from creating new cell walls and amino acids, and lowers their antioxidant levels.15 More recently, a 2024 review broadly confirmed that berberine has anti-pathological capabilities.52 And although much of the research on berberines impact on intestinal and gut microbiome health is still in progress, studies have supported the anecdotal evidence that berberine may be a potent anti-diarrheal agent.2 As an anti-inflammatory Berberines anti-inflammatory effects come into play through the modulation of multiple signaling pathways

Recently, mesoporous silica nanospheres (MSNs) as nano-carriers attracted much attention due to chemically modifiable surfaces, high surface area, characteristic nanostructure, biocompatibility and a large load capacity 32,33,34

Targeting lipid metabolism in metastatic prostate cancer