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And simply adding membranes everywhere is often too costly or operationally demanding

These processes would amplify one another in positive feed-forward loops, leading to persistent impairments of the maturation and function of local parvalbumin-GABAergic neurons microcircuits and myelinated fibers of long-range macrocircuitry

Under normal circumstances, the majority of CpG dinucleotides are methylated, but aberrations in DNA expression caused by the promoter hypermethylation of CpG islands can lead to carcinogenesis

Exposure to pro-oxidant stimuli usually induces Nrf2 activation and upregulation of antioxidant enzyme expression through binding to the antioxidant response element (ARE), localized in the antioxidant enzyme gene promoters