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When that layer takes on oxidative damage, a lot of things downstream start to suffer

In a healthy body, glutathione acts as the ultimate biological shield, protecting delicate cellular architecture from the constant threat of highly reactive molecules known as free radicals or reactive oxygen species (ROS)

ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung

But proving this requires a tremendous amount of additional research that has only just begun.36 The bottom line is that both NR and NMN can increase levels of NAD+ in the human body.8 Which one you ultimately choose may have to do with your tolerance for either