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The German PCS-guidelines emphasize that no routinely available parameters can confirm or exclude PCS ( It is widely accepted for both conditions that no single, definitive cause exists ( Diagnostic challenges Patient symptoms following COVID-19 and in individuals with PI-IBS often remain unexplained by objective findings in routine testing, highlighting the complexity and evolving nature of these conditions

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Annals of Nutrition and Metabolism

pneumoniae infection induces memory in respiratory epithelial cells, which enhances bacterial adhesion and facilitates infection upon reinfection ( Figure 1 4 The dual role of trained immunity Trained immunity may represent an evolutionarily primitive form of immune memory