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Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

A 2016 study published in Nature Medicine demonstrated that MOTS-c administration improved insulin sensitivity and reduced diet-induced obesity in mouse models, even when started after metabolic dysfunction was already established

174 According to a different study, an amphibian-derived peptide homodimer OA-GL17d showed potential ability to promote skin wound regeneration through the miR-663a/TGF-1/Smad axis

The peptide is highly stable and has good bioavailability, which lends credibility to this theory