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As a consequence, IEC metabolism shifts to anaerobic pathways leading to elevated mucosal oxygen concentrations, thereby facilitating colonisation by facultative anaerobes which are responsible for gut-associated inflammation (Byndloss et al

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The complexity deepens when we consider that the majority of AD patients, especially in the elderly population, carry at least one of these vascular risk factorsapproximately 65% of individuals aged 65 and 80% of those aged 85 (Lokovic et al