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Hybrid nanocarriers co-delivering curcumin with siRNA (e.g., against survivin) demonstrate augmented tumor penetration and synergistic apoptosis induction in ovarian and cervical cancer models [27]

While the capsule is generally safe, diabetic patients should consult their endocrinologist or general physician before adding this supplement to their regimen to ensure it does not interfere with their current antidiabetic medications

PLoS ONE 11:e0153685

However, Mendelian randomization studies gave inconsistent results whereas intervention-studies with UA-lowering therapies, particularly with XOR inhibitors, were disappointing in terms of reduction of incident CVD or CVD-related outcomes even though these therapies consistently reduced UA level