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Without published data, we simply do not know whether FTPP worked in humans, whether the side effects were manageable, or whether any positive signals emerged

A population-based retrospective cohort study covering all live births in Denmark from 1996 to 2009, reported on 1,800 live births whose mothers used omeprazole during the first trimester of pregnancy and 837,317 live births whose mothers did not use any proton pump inhibitor

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Currently, the development of drugs targeting CD38 inhibition for the treatment of these conditions is in its early stage, and further preclinical and clinical studies are required to determine the effectiveness of these treatments