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Vitamin B12 Injections Intramuscular injections are the standard treatment Initial loading phase followed by maintenance doses Often required for life Oral Vitamin B12 High-dose oral supplementation may be effective in some patients Suitable for those who cannot tolerate injections Monitoring Regular blood tests Neurological assessment Monitoring response to therapy Most patients experience rapid improvement in symptoms after starting treatment

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When tirzepatide was combined with intensive lifestyle intervention (structured diet, exercise, and behavioral counseling), participants achieved a total mean weight loss of 26.6%, roughly 64 pounds, over 84 weeks