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These astrocytic cells undergo pathophysiological changes, propelling disease progression and altering synaptic transmission

Les antioxydants liminent les radicaux libres dans le corps et participent ainsi rduire le stress oxydatif

Antagomirs and CRISPR/Cas9-based editing systems enable tissue-specific miR-155 modulation, offering targeted therapeutic potential

Expert Rev Neurother 17:227237 Valls A, Evers MM, Stam A, Sogorb-Gonzalez M, Brouwers C, Vendrell-Tornero C, Acar-Broekmans S, Paerels L, Klima J, Bohuslavova B, Pintauro R, Fodale V, Bresciani A, Liscak R, Urgosik D, Starek Z, Crha M, Blits B, Petry H, Ellederova Z, Motlik J, van Deventer S, Konstantinova P (2021) Widespread and sustained target engagement in Huntingtons disease minipigs upon intrastriatal microRNA-based gene therapy