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The detection wavelength was set at 210 nm with a UV detector at a flow rate of 0.6 mL/min and a column temperature of 60 C

Many patients experience significant weight loss within the first few weeks of therapy

doi: 10.1182/blood-2006-12-063933 30 ShiYNZhuNLiuCWuHTGuiYLiaoDFet al

The partial Mayo score is a composite index of 3 disease activity variables (stool frequency, rectal bleeding, and Physician Global Assessment, each scored on a scale from 0 to 3 (higher scores indicate greater disease activity.)) VISIBLE 1 TRIAL EXPLORATORY END POINTS: PHARMACOKINETICS ENTYVIO PEN & IV PROVIDE CONSISTENT DRUG TROUGH LEVELS ENTYVIO PEN & IV PROVIDE CONSISTENT DRUG TROUGH LEVELS PK data for IV and pen were not directly compared and do not imply efficacy or safety