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As these patients were most likely classified as moderate progressors, the results suggested that 50 mg methylcobalamin injections could be beneficial for patients with ALS in the early stage and with moderate progression rate, the researchers wrote

Half-lives were estimated 100 and 200 h for diazepam and nordiazepam respectively, while half-lives of oxazepam and temazepam were considerably lower (36 and 32 h respectively), which is probably a consequence of few times higher quantum yields

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