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For a lean or sub-160 lb South Asian, where chronotropic sensitivity is highest, 0.3 mg is the floor and the cautious starting point

J AOAC Int 93:18291835 Gracia-Lor E, Sancho JV, Hernndez F (2011) Multi-class determination of around 50 pharmaceuticals, including 26 antibiotics, in environmental and wastewater samples by ultra-high performance liquid chromatographytandem mass spectrometry

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Following initiation of therapy and after each dose adjustment, monitor hemoglobin weekly until the hemoglobin level is stable and sufficient to minimize the need for RBC transfusion