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Pernicious anemia is an autoimmune disease that attacks and potentially destroys gut cells so that intrinsic factor is not present, which is crucial for vitamin B12 to be absorbed

Sources: Anisimov VN, et al

This ethnic difference is attributed in part to a higher concentration of B12 binding proteins, most notably the transport protein haptocorrin

Lilly's oral GLP-1, orforglipron, delivered superior blood sugar control and weight loss compared to oral semaglutide in head-to-head type 2 diabetes trial published in The Lancet [press release]