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In conclusion, our study revises the traditional view of GSH as a global protective antioxidant against protein oxidation under physiological condition and demonstrates that GSH depletion through enhanced degradation leads to selective protein oxidation

Furthermore, preclinical studies on regenerative medicine therapies that utilize cells, biomaterials, growth factors, platelet-rich plasma (PRP), and biological agents have demonstrated their promise in repairing degenerated lumbar discs