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In the context of ischemic myocardium, particularly following reperfusion, ROS can directly impair cell membranes, leading to cellular death and significant damage to the heart [59]

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We conduct the first genome-wide CRISPRi and CRISPRa screens in human neurons based on a panel of cellular phenotypes, and CROP-seq screens to uncover transcriptional fingerprints of genes associated with neurodegenerative diseases

HGF activation of the Met receptor has also been shown to mediate dendritic arborization and neurogenesis in cultured hippocampal neurons [86] and facilitate memory consolidation and retrieval in memory compromised animal models [87-90]