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Since the Vina docking calculations predict the binding modes, orientations, and conformations of small molecule inhibitors within the catalytic domain of the target protein, the docked output for the 1-MQ analog1j with an IC 50 value of 1.2 M was used to generate the predicted inhibitor-binding mode of 1j using the Auto Dock Tools (ADT) molecular graphics program

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10.3390/ijms20174314 197

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Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor

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To further assess the impact of multiple NCOA4 383522 motifs on GATE16 binding, we generated single and double mutants of the identified motifs

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