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Nevertheless, the utilization of reserpine as a pharmaceutical agent is constrained due to its propensity to induce hepatic and other organ damage through the process of excess free radical production and oxidative stress ( 6 )

Science 369 , 10101014 (2020)

Pantothenate biosynthesis is necessary for the virulence of Mtb , and it was found that Mtb pantothenate auxotrophy with panC (Rv3602c) and panD (Rv3601c) gene defects was highly attenuated in mice infection models [185]

This study was supported by grants for the major project of the National Science Foundation of China (grantnumber: 31860489 to MZ) and the China Agriculture Research System of the Ministry of Finance (MOF) and the Ministry of Agriculture and Rural Affairs (MARA