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While immune cells can recognize and eliminate senescent cells, many of these cells can evade immune detection in aging and disease states, allowing them to persist and negatively impact the function of neighboring cells (Augustin and Koh, 2024

It was later noted in the different tumor models that although most tumor cells exhibited limited growth potential, a portion succeeded in producing a significant number of new tumors [157]

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The WADA ban clarifies international consensus: IGF-1 LR3 is considered a performance-enhancing substance with sufficient evidence of misuse to justify blanket prohibition in competitive sport