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Viral proteins, such as the matrix protein of human parainfluenza virus 3 (HPIV3) and PB1-F2 of influenza A virus (IAV), directly interact with autophagy-related proteins like ATG8 and mitochondrial Tu translation elongation factor (TUFM) to induce ubiquitin-independent mitophagy

Other studies should be conducted to explore antioxidant substances in the treatment of melasma, or in the prevention of its recurrence

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For instance, during mitochondrial respiration, the electron transport chain occasionally leaks electrons that react with molecular oxygen to form superoxide radicals (O2) [22]