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Hasmann, M

doi: 10.1128/mSphere.00106-18 38 PiskolF.NeubauerK.EggersM.BodeL

While the effect of KG accumulation on immunity in colorectal cancer remains unreported, in cholangiocarcinoma, -KG accumulation activates the OXGR1 receptor on macrophages, which in turn triggers the MAPK signaling pathway, suppresses macrophage antigen presentation, and enhances immunosuppression (324)